WebbOne of the most important pleiotropic effects of endorphins is regulation of the immune system, ... Thus, hippocampal dentate neural stem cells may be a potential benefit of endorphins in neuropathy associated with cranial neurogenesis disorders in adults, an important target. References. Gilbert DL, Horn PS, Kang PB, Mintz M, Joshii SM, ... Webb30 juni 2015 · Pleiotropy arises when a locus influences multiple traits. Rich GWAS findings of various traits in the past decade reveal many examples of this phenomenon, suggesting the wide existence of pleiotropic effects. What underlies this phenomenon is the biological connection among seemingly unrelated traits/diseases. Characterizing the molecular …
Free Full-Text Pleiotropic Effects of Modified Citrus Pectin - MDPI
WebbTo dissect the genetic basis of cotton breeding in China, a 16-parent cotton MAGIC population was newly developed in this study. 25 pleiotropic genomic loci were identified by GWASs, providing an explanation for the simultaneous changes between cotton yield and fiber quality. The narrow genetic structure of Chinese cotton cultivars was also … Webb9 mars 2024 · In their model, the fitness effects of mutations form a continuum, such that the mutations accumulated in the home environment may provide a range of pleiotropic … cross country outreach
Comparative Analysis of the Preventive Effects of Canagliflozin, a ...
WebbThe noncausal theory supports the premise that clinical benefits are related primarily to pleiotropic effects of statins (endothelial function, inflammation, coagulation and plaque … Webb5 maj 2024 · In this review, we will present the cardiovascular and metabolic effects of GLP-1 agonists in type 2 diabetes, beyond serum glucose control. 2. Mechanism of action of GLP-1 hormone and its pleiotropic effects. Multiple organ dysfunction, with macrovascular and microvascular complications, represent an effect and also a … Webb7 nov. 2011 · Many patients do not achieve their lipid targets on current treatment regimens, and discontinuing or modifying statin therapy based on lipid targets alone potentially ignores the potential valuable cardio- and vasculo-protective pleiotropic properties of these compounds and the benefits they may provide to patients in addition … bug life hopper