Tīmeklis2024. gada 12. febr. · A variety of animal models of diabetes mellitus (DM) are required to study the genetics and pathophysiology of DM. We established a novel rat strain showing nonobese type 2 diabetes with enlarged kidneys from the LEA.PET- pet congenic strain and named it Diabetes with Enlarged Kidney (DEK). The body … Tīmeklis2012. gada 10. dec. · The aim of this study was to investigate pathophysiological alterations and oxidative stress in various stages of streptozotocin (STZ)‑induced diabetes mellitus (DM) in rats. Male Sprague-Dawley rats (120) were randomized into DM and control groups. Body mass, plasma glucose, glycated hemoglobin (HbA1c), …
Streptozotocin-induced diabetic models in mice and rats
TīmeklisStreptozotocin-induced diabetic models in mice and rats. Streptozotocin (STZ) is an antibiotic that can cause pancreatic β-cell destruction, so it is widely used … Tīmeklis2024. gada 8. nov. · Diabetic nephropathy (DN) is the main factor leading to end-stage renal disease (ESRD) and subsequent morbidity and mortality. Importantly, the prevalence of DN is continuously increasing in developed countries. Many rodent models of type 1 and type 2 diabetes have been established to elucidate the … godfather aveleyman
50 week ultrasound imaging and ultrastructural abnormalities …
Tīmeklis2024. gada 15. aug. · Streptozotocin (STZ) was used to induce diabetes in rats. According to several studies 3 , 43 , 44 , different amounts of STZ injection combined with normal chow and a high-fat diet can simulate ... Tīmeklis3.2. Establishment of a Diabetic Rat Colony, Hos:ZFDM-In 2008, during maintenance of the above-mentioned ZF rat colony, we incidentally identified one 25-week-old fa/fa male rat exhibiting diabetes (Figure … Tīmeklis2024. gada 21. maijs · The induction of diabetes in rats was by a single intraperitoneal injection of STZ (65 mg/kg body weight) while C. volubile extract was administered orally to diabetic and non-diabetic animals, at the doses of 50, 100 and 200 mg/kg body weight for 14 days. Metformin (100 mg/kg body weight) served as positive control. godfather automatic 907