Pseudopodium-enriched atypical kinase 1
Weba cytoskeleton-associated kinase, pseudopodium-enriched atypical kinase 1 (PEAK1). PEAK1 is a 190-kDa nonreceptor tyrosine kinase that localizes to actin filaments and focal adhesions. PEAK1 under-goes Src-induced tyrosine phosphorylation, regulates the p130Cas-Crk-paxillin and Erk signaling pathways, and operates downstream WebSep 23, 2024 · Pseudopodium-enriched atypical kinase 1 (PEAK1) has been reported to be upregulated in human malignancies and is correlated with a poor prognosis. Enhanced …
Pseudopodium-enriched atypical kinase 1
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Weba cytoskeleton-associated kinase, pseudopodium-enriched atypical kinase 1 (PEAK1). PEAK1 is a 190-kDa nonreceptor tyrosine kinase that localizes to actin filaments and … WebPEAK1 15:77100656-77420144 Reverse strand gene: pseudopodium enriched atypical kinase 1 Also known as: sgk269, KIAA2002, ENSG00000173517 Function: Probable catalytically inactive kinase. Scaffolding protein that regulates the cytoskeleton to control cell spreading and migration by modulating focal adhesion dynamics (PubMed:23105102, …
WebMay 29, 2024 · Pseudopodium-enriched atypical tyrosine kinase 1 (PEAK1, Sgk269) is a newly discovered non-receptor tyrosine kinase ubiquitously expressed in all tissues, … WebPseudopodium-enriched atypical kinase 1 (PEAK1) has been reported to be upregulated in human malignancies and is cor - related with a poor prognosis. Enhanced PEAK1 expression facilitates tumor cell survival, invasion, metastasis and chem- oresistance. However, the role of PEAK1 in breast cancer is unclear.
WebPseudopodium-enriched atypical kinase 1 (Peak1; KIAA2002, or sgk269) is a ubiquitous non-receptor tyrosine kinase that belongs to the NFK3 family. It interacts with actin filaments via its N-terminal actin-targeting region. Web开馆时间:周一至周日7:00-22:30 周五 7:00-12:00; 我的图书馆
WebJan 4, 2013 · Abstract Pseudopodium-enriched atypical kinase 1 (PEAK1) is a recently described tyrosine kinase that associates with the actin cytoskeleton and focal adhesion …
WebDec 1, 2014 · PEAK1 (pseudopodium-enriched atypical kinase 1, KIAA2002, sgk269), a member of the new kinase family three (NKF3), is ubiquitously expressed in multiple tissues and plays a major role in normal physiology [5]. In 2010, PEAK1 was first identified as an important cytoskeletal regulatory kinase involved in some signaling pathways to regulate … esgaming 750 watt power supplyWebName pseudopodium-enriched atypical kinase 1 Synonyms 1110049L02Rik, C230081A13Rik, NKF3 kinase family member Feature Type protein coding gene IDs … esgaming gaming computer casehttp://www.informatics.jax.org/marker/MGI:2442366 esg analyst internshipWebAug 1, 2024 · The pseudopodium enriched atypical kinase 1 (PEAK1), which is an oncogenic nonreceptor tyrosine kinase controlling cellular migration and proliferation, was found to be upregulated in breast cancer, colon cancer, and pancreatic cancers ( 31, 32 ). es game of skateWebApr 8, 2024 · Pseudopodium-enriched atypical kinase 1 mediates angiogenesis by modulating GATA2-dependent VEGFR2 transcription. ... thereby priming the proteins for further phosphorylation by casein kinase 1 ... finishing touch coversWebFeb 2, 2024 · These proteins, pseudopodium-enriched atypical kinase 1 (PEAK1, Sugen kinase 269, or SgK269) and pragmin (Sugen kinase 223 or SgK223), act as scaffolds in growth factor signaling pathways, and both contain a kinase fold with degraded kinase motifs at their C termini. esg analyst sustainability integrationWebJul 27, 2011 · Pseudopodium-enriched atypical kinase 1 1 publication. Sugen kinase 269; Tyrosine-protein kinase SgK269; Gene names. Name. Peak1. Synonyms. Kiaa2002, Sgk269. Organism names. Organism. ... PS00109 PROTEIN_KINASE_TYR 1 hit; Pfam. View protein in Pfam; PF00069 Pkinase 1 hit; SMART. View protein in SMART; SM00220 S_TKc 1 hit; finishing touch craft show