Phospho stat1
Phospho-Stat1 (Tyr701) (58D6) Rabbit mAb detects endogenous levels of Stat1 only when phosphorylated at tyrosine 701. The antibody detects phosphorylated tyrosine 701 of p91 Stat1 and also the p84 splice variant. It does not cross-react with the corresponding phospho-tyrosines of other Stat proteins. Species Reactivity: Human, Mouse Web2 days ago · Phosphorylation of four kinases, namely Protein tyrosine kinase 2 (PYK2), Glycogen synthase kinase-3 (GSK3α/β), Signal transducer and activator of transcription 1 (STAT1) and Signal transducer ...
Phospho stat1
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WebThe expression of phosphorylated signal transducer and activator of transcription 1 (p‑STAT1), one of the IFN‑γ signaling pathway molecules, was analyzed using … WebCell-Based phospho-STAT ELISA Samper Kit for detecting phospho-STAT1 (pTyr 701), phospho-STAT3 (pTyr 705), and phospho-STAT5 (pTyr 694) in cultured cell lines 检测培养 …
WebSee all STAT1 primary antibodies Description Mouse monoclonal [M135] to STAT1 (phospho Y701) Host species Mouse Specificity The antibody detects 84 and 91 kDa … WebSTAT1 is known to regulate several genes which are involved in cell growth, apoptosis, immune responses, and lipid metabolism. Further, STAT1 plays an important role in mediating cell viability in response to different cell stimuli and pathogen exposure. The STAT1 gene is located on chromosome 2.
WebJan 9, 2024 · The addition of ruxolitinib inhibited STAT1 phosphorylation and to a lesser extent STAT3 phosphorylation. Ruxolitinib treatment prevented NSCLC cells from enhancing PDL-1 expression in response to ... WebOct 30, 2024 · STAT1 expression can rescue the erythroid phenotype caused by arhgef12 knockdown in zebrafish. Human STAT1 produces two splicing variants that differ at their carboxy terminus. ... Phospho-flow histograms of phospho-p38 on pro-erythroblasts with different rs10892563 genotypes. Phosphorylated p38 was stained with anti-pT180/pY182 …
WebPhospho‑STAT1 expression as a potential biomarker for anti‑PD‑1/anti‑PD‑L1 immunotherapy for breast cancer Phospho‑STAT1 expression as a potential biomarker for anti‑PD‑1/anti‑PD‑L1 immunotherapy for breast cancer Authors
WebAug 15, 2024 · Membranes were then incubated overnight at 4°C with primary antibodies specific for p65, IκBα, IKKβ, phospho-IKKβ (Abcam, Cambridge, UK), phospho-Stat1 … garden centre silk willoughbyWebSTAT1 is activated to regulate gene expression in response to extracellular signaling polypeptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, STAT1 enters the nucleus … garden centres haywards heath areaWebWestern blot analysis of extracts from HeLa, A20, and PC-12 cells, untreated or treated with Human Interferon-α1 (hIFN-α1) #8927 (10 ng/ml, 30 min), using Phospho-Stat1 (Tyr701) (D4A7) Rabbit mAb (upper) or Stat1 Antibody #9172 (lower). black mtn burger lincoln nhWebAug 15, 2024 · Membranes were then incubated overnight at 4°C with primary antibodies specific for p65, IκBα, IKKβ, phospho-IKKβ (Abcam, Cambridge, UK), phospho-Stat1 (Santa Cruz, Dallas, TX), Stat1 (ThermoFisher, Wilmington, DE), or actin (LI-COR Biosciences, Lincoln, NE) at recommended dilutions. Membranes were washed and subsequently … garden centres ilkley areaWebPhospho-Stat1 (Tyr701) Antibody detects endogenous levels of Stat1 only when phosphorylated at tyrosine 701. The antibody detects phosphorylated tyrosine 701 of p91 … black mt golf courseWebAnti-phospho-STAT1 (Tyr701) Antibody is a Rabbit Polyclonal Antibody for detection of phospho-STAT1 (Tyr701) also known as Transcription factor ISGF-3 components p91/p84 & has been validated in WB. Research Category Epigenetics & Nuclear Function. Research Sub Category Transcription Factors. garden centre shirley solihullWebMar 31, 2024 · Background: Unphosphorylated signal transducer and activator of transcription 1 (U-STAT1) has been reported to elicit a distinct gene expression profile as compared to tyrosine-phosphorylated STAT1 (P-STAT1) homodimers. However, the impact of U-STAT1 on the IFNγ-induced immune response mediated by P-STAT1 is unknown. By … garden centre shooters hill welling