WebASAH2 is a type II integral membrane protein that can be cleaved to yield a soluble secreted protein and acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form ... WebNote. Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation,go to u00a0How to contribute
ASAH2 Polyclonal Antibody (PA5-20575) - Thermo Fisher Scientific
Web13 ott 2024 · Enables dihydroceramidase activity and phytoceramidase activity. Involved in response to organic substance and sphingolipid metabolic process. Located in extracellular space; mitochondrion; and plasma membrane. Is integral component of plasma membrane. Colocalizes with membrane raft. Orthologous to several human genes including ASAH2B … WebExpression of ASAH2 in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again. ASAH2. SECTIONS. flights to youngstown
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WebN-acylsphingosine amidohydrolase 2 (ASAH2), also known as neutral ceramidase (N-CDase, NCDase), is a key regulator of sphingolipid signaling metabolites. ASAH2 is … WebQ9NR71 - ASAH2 - Neutral ceramidase - Function. Plasma membrane ceramidase that hydrolyzes sphingolipid ceramides into sphingosine and free fatty acids at neutral pH (PubMed:10781606, PubMed:16229686, PubMed:26190575). Ceramides, sphingosine, and its phosphorylated form sphingosine-1-phosphate are bioactive lipids that mediate … WebFIGURE 2 Asah2 gene and neutral ceramidase expression in wild-type mouse tissues. A, Asah2 gene expression in mouse tissues was determined by real-time PCR. Total RNA … flights to yuba city